Home > Research > Volunteer > Research studies

Research studies

  • Self-Gated, Motion-Resolved Whole Heart Coronary MRA with Isotropic Resolution.

Principle Investigator: Debiao Li, PhD

The purpose of this research study is to examine whether or not MRI acan be used to diagnose diseases in the blood vessels of the heart. MRI techniques for imaging the vessels of the heart are still in progress and the resuls of the srudy will provide important information on the ability of using MRI for diagnosing blood vessel disease of the heart and will lead us to future improvements of MRI techniques. As well as, to collect data from your exam to help researchers determine whether or not MRI can be used to diagnose coronary artery disease.

  • Magnetic Resonance Imaging of Coronary Arteries at 3T.

Principle Investigator: Debiao Li, PhD

To aid in the development of new ways of examinign the blood vessels of the heart.

  • FMRI BOLD contrast: Relationship to Cerebrovascular Tone.

Principle Investigator: Todd Parrish, PhD

The purpose of this research study is to determine how brain blood flow changes:
  1. after breathing pure oxygen
  2. after having a diuretic (Furosemide), which causes you to create urine
  3. in the presence of cerebrovascular disease
  4. after having a small amount of caffeine
  5. during the performance of simple tests
  • Non-Invasive Stain for AD Using High Resolution Magnetization Transfer Imaging.

Principle Investigator: Todd Parrish, PhD

The purpose of this research study is to use MRI to look at changes in the brain in patients with probable Alzheimer’s Disease, primary progressive aphasia, and normal control subjects of similar age range.

  • MRI for Detecting Functionally Important Coronary Artery Stenosis at Rest.

Principle Investigator: Rohan Dharmakumar, PhD

The purpose of this study is to examine whether or not a technique called 4D phase-resolved steady-state free precession (SSFP) magnetic resonance can detect changes in blood volume and oxygenation in the heart of healthy volunteers using MRI techniques. Evaluating blood volume and oxygenation changes in the heart may improve our understanding of the human heart and may lead to better MRI methods for studying the progression of coronary artery disease.

  • Evaluation of Investigational MRI Software and Hardware.

Principle Investigator: James Carr, MD

The purpose of this study is to help researcher develop the MRI system so that it can take clearer and more accurate pictures.

  • Development and Validation of Improved Methods for Evaluation of Myocardial Infarction using a 3 Tesla MRI System.

Principle Investigator: James Carr, MD

The purpose of this research study is to examine whether or not an MRI scanner operating at a higher field strenght os 3 Tesla (3T) can detect the tissue damaged better than the 1.5T, as well as faster.

  • Computed Tomographic Angiography (CTA) of the Coronary Arteries Using 64-Slice Multidetector CT Scanner.

Principle Investigator: James Carr, MD

The purpose of this study is to see if a newly developed 64-slice computed tomography (CT) scanner can image the coronary arteries as accurately as the current imaging standard, which is an invasive technique called coronary angiography or cardiac catheterization.

  • To Compare Computed Tomographic Angiography (CTA) to Magnetic Resonance Angiography (MRA) for Detecting Coronary Artery Disease.

Principle Investigator: James Carr, MD

The purpose of the study is to compare coronary CT Angiography (CTA) with coronary Magnetic Resonance Angiography (MRA) to evaluate subjects with coronary artery disease.

  • The Evaluation of Valvular Heart Disease in Patients Anticipating Surgical Correction Using 64-Slice Miltidetector Computed Tomography.

Principle Investigator: James Carr, MD

The purpose of the study is to see if a newly developed 64-slice computed tomogrphy (CT) scanner can detect valvular disease of the heart as accurately as the current imaging standard, which is an invasive technique called coronary angiography or cardiac catheterization.

  • Atherosclerotic Plaque Characterization Using High-field MRI.

Principle Investigator: Timothy J. Carroll, PhD

This study is being done to look at the ability of magnetic resonance imaging (MRI) to detect the composition of the plaque inside the arteries. You will be asked to undergo this study only if you have been diagnosed with atherosclerotic vascular disease and will undergo a clinical MRI at Northwestern Memorial Hospital as part of your care.

  • Improved MR Imaging of Neurovascular Disease.

Principle Investigator: Timothy J. Carroll, PhD

The purpose of this study is to develop a technique to accurately image blood vessels of the brain using MRI. This study will compare a research procedure with a standard cerebral angiogram.

  • Self-Gated Cardiac MRI.

Principle Investigator: Andrew Larson, PhD

The purpose of this research study is to examine whether or not clear images of the heart and cardiovascular system can be produced if the ECG and breath-holding is not used during the MRI scan. This could make cardiovascular MRI easier to perform for both patients and medical staff.